When we combined subjects with acute DILI from the US DILIN cohort and those with ALF due to drugs other than Apap, to AIH, or to acute hepatitis B [which groups are biologically and patho-physiologically more similar to the acute DILIN subjects], we found a total of three analytes that were significantly different between those who died vs those who lived, namely, serum albumin, IL-6 and IL-8, and one analyte that showed a strong trend towards significance, namely, RANTES (p = 0.056). This evidence concerns the gene CXCL8 and autoimmune hepatitis.