(A) Nude mice bearing MDA-MB-468, BT-474 or JIMT-1 tumors were imaged with 89Zr-trastuzumab 48 h p.i. (B) Tumor VOIs showing significant uptake in HER2+ tumors, but no uptake in MDA-MB-468 (HER2-) tumors (C). Here, ERBB2 is linked to neoplasm.