We further demonstrated that high UCHL1 expression was positively associated with NB differentiation, indicating by higher UCHL1 expression in ganglioneuroblastomas (GNB)/ganglioneuromas (GN) and well-differentiated NB than poorly differentiated NB, as well as the positive correlation between UCHL1 expression and differentiation markers. The gene discussed is UCHL1; the disease is ganglioneuroma.