In addition, both LH/FSH (OR = 1.20, 95% CI = 1.01–1.43, P = 0.04) and the testosterone level (OR = 1.56, 95% CI = 1.27–1.90, P < 0.001) were positively associated with hyperuricemia in the adjusted model (Table 3). The gene discussed is PLOD1; the disease is hyperuricemia.