CD81 and paracoccidioidomycosis: Another univariate analysis indicated that the following factors were closely associated with OS (P < 0.05): ISS stage III; age ≥60 years; beta‐2‐MG>5.5 mg/L; creatinine>176.8 μmol/L; CD117(−); CD81(+) (Table 4).Next, characteristics that were found to significantly affect the survival of PCM patients in the univariate analyses were further evaluated in a multivariate analysis.