MAPT and Alzheimer disease: Structural connectivity correlated with tau deposition in the bilateral hippocampi (Figure 3) and showed increased connectivity of the corpus callosum (CC), inferior longitudinal fasciculus (ILF), cingulum, corticospinal tract (CST), medial lemniscus (ML), and superior/middle cerebellar peduncle (SCP/MCP; FDR = 0.0025) in the CN group, but showed decreased connectivity of the CC, superior longitudinal fasciculus (SLF), inferior fronto‐occipital fasciculus (IOF), uncinate fasciculus, CST, ML, SCP/MCP, and inferior cerebellar peduncle (ICP; FDR = 0) in the AD‐spectrum group.