Structural connectivity correlated with tau deposition in the temporal lobes (Figure 4) and showed increased connectivity of the CC, ILF, CST, and SCP/MCP (FDR = 0.0023) in the CN group, but showed decreased connectivity of the CC, IOF, CST, and MCP (FDR = 0.015) in the AD‐spectrum group. The gene discussed is CXCR1; the disease is Alzheimer disease.