HMBOX1 and atherosclerosis: The lack of HMBOX1 in HUVECs can induce cell apoptosis and inhibit cell autophagy, which are indispensable for HUVEC survival.17 In addition, HMBOX1 is essential for the maintenance of endothelial function and has the potential to be a novel therapeutic target for atherosclerosis (AS).18 However, the precise role of HMBOX1 in the context of anti‐inflammatory and anti‐oxidative effects of TDD in EA.hy926 cells remains unknown.