Variations of the glucose tolerance test are employed clinically to test for diabetes, insulin resistance, impaired beta‐cell function, or other disorders of carbohydrate metabolism.8, 9 The hyperinsulinemic‐euglycemic clamp method is generally considered the “gold standard” for evaluation of insulin sensitivity, but this test is more invasive, time‐consuming, and costly. The gene discussed is INS; the disease is diabetes mellitus.