However, our results were not consistent with the results from a previous study about IL-36α in SLE with the only elevated level of IL-6, instead of IFN-γ and IL-17A (31), which may be related to IL-36α concentration, detection kit and cell population because the target cells and the intensity of IL-36α are different in different autoimmune inflammatory diseases. The gene discussed is IL36A; the disease is systemic lupus erythematosus.