PPAR–α and PPAR–γ have similar neurophysiological functions that include regulation of the redox response, neuroinflammation, neurogenesis, cellular differentiation, as well as secondary functions in the regulation of cognition, anxiety, and emotional behavior (Bordet et al., 2006; Bright et al., 2008; Panlilio et al., 2012; Fidaleo et al., 2014). The gene discussed is PPARG; the disease is Anxiety.