There was no significant difference in expression of IFNA and IFNB between the Control and Cuo-IRF7 cells upon infection despite upregulation of IRF7 upon infection in each cell line (Control: 1.44-fold, FDR = 0.039; Cuo-IRF7: 1.31-fold, FDR = 0.098, DESeq2). The gene discussed is IRF7; the disease is infection.