The same was demonstrated in renal clear cell carcinoma cell lines (Liu et al., 2010) and basal-like breast cancer (Dong et al., 2013), in which DNMTs were recruited by Snail through G9a and SUV39H1, two HMTs that establish H3K9me3, leading to aberrant methylation of FBP1 promotor (Dong et al., 2013; Li and Li, 2015). This evidence concerns the gene FBP1 and breast cancer.