NR3C2 and endothelial dysfunction: The beneficial effect of finerenone on the restoration of endothelial function in MWF by an increase in peNOSSer1177/eNOS, and thus in both basal and stimulated NO availability, is in accordance with previous data demonstrating that MR signaling contributes to endothelial dysfunction (Quaschning et al., 2001; Virdis et al., 2002; Sanz-Rosa et al., 2005; Bolignano et al., 2014).