ADAM33 and cardiovascular disorder: There are, however, several potentially interesting candidate genes for atherosclerosis in each of these linked regions, for instance, among the genes under the base to base linkage peaks at chromosome 19 and 20, several genes have been implicated in the pathogenesis of cardiovascular disease, including FCAR, TNNT1, OSCAR, FPR2 under the peak at chromosome 19 and ADAM33, TRIB3, HSPA12B under the peak at chromosome 20.