Criteria for inclusion in a neonatal sepsis clinical trial Clinical sign (temperature instability, cardiovascular instability, skin symptoms, respiratory instability, gastrointestinal symptoms, non-specific symptoms) Laboratory signs: Low/high WBCs, I/T-ratio > 0.2, Platelet count < 100, CRP > 15 mg/L or PCT > 2 ng/mL, glucose intolerance and metabolic acidosis. This evidence concerns the gene CRP and Sepsis.