A Kaplan–Meier survival curve estimated that the patients with HCC who were positive for both H3K36me3 and CK19 had the lowest 5-year survival rate, which was significantly lower than that of patients with HCC who were positive for either CK19 or H3K36me3 alone (P = 0.0027). Here, KRT19 is linked to hepatocellular carcinoma.