Further studies are recommended on the peptide binding assays, the design of polyepitope constructions including E5, E6 and E7 epitopes, the expansion of the minimal CTL epitopes to longer peptides (SLPs), the use of various adjuvants, involvement of delivery routes, mouse immunization with the designed constructs, evaluation of immune responses such as cytokines, antibodies, CTLs and tumor growth for finding the best construct for clinical trials. Here, ARHGEF15 is linked to neoplasm.