CCL27 and colitis: To address the functional relevance of these findings in the context of type 1 mucosal inflammation, we induced acute colitis in T-betΔNCR+ILC mice with DSS.41 It has previously been shown that ILC2s play a protective role in DSS colitis,42 therefore, we hypothesised that the expansion of ILC2s observed in mice lacking T-bet in the ILC compartment would be protective from colitis.