It is worth noting that, although cTnI and cTnT are the best validated, several other direct and indirect biomarkers such as myoglobin, ischemia-modified albumin (IMA), glycogen phosphorylase isoenzyme BB, copeptin (C-terminal proAVP), fatty acid-binding protein (FABP), B-type natriuretic peptide (BNP)—mostly measured as NT-proBNP—and myeloperoxidase have been identified in acute myocardial infarction (AMI) patients, and could be the targets of future RDTs. The gene discussed is NPPB; the disease is acute myocardial infarction.