After 30 days, the only plants to show symptoms characteristic of a systemic CPMV infection (curling and mottled yellowing of the upper leaves) were those coinfiltrated with pEAQ-RNA-1-Int and pEAQ-RNA-2 (Fig. 5), while the plants infiltrated with pEAQ-RNA-1-Int-GAD or pEAQ-RNA-1-Int-AAA in the presence of pEAQ-RNA-2 were symptomless, as were control plants coinfiltrated with pBinP32E and pEAQ-RNA-2. The gene discussed is INTU; the disease is infection.