While altered TSPO expression on astrocytes may contribute to the differences, the post-mortem findings of unaltered astrocytic but elevated microglial markers (Trepanier et al., 2016), including elevated TSPO binding (Kreisl et al., 2013), are more suggestive of a microglia activity increase in schizophrenia. The gene discussed is TSPO; the disease is schizophrenia.