APOE and atherosclerosis: These included ABCA1, ABCG1, APOC1, APOE, APOL2, BMP1, CETP, PLTP, PRKAA1, and SREBF1. In other words, these overlapping pathways and their component genes are both differentially regulated in macrophages from symptomatic plaques and have been implicated in pathways associated with complications of atherosclerosis in GWAS.