SAP130 and myocardial infarction: SAP130, an endogenous ligand for Mincle, is normally related with assembling the spliceosome and consisting of the U2 small nuclear ribonucleoprotein‐associated protein complex.40 Under steady condition, neither SAP130 nor Mincle is expressed at a high level.41 We noted that there was an increase in SAP130 release within the PVN post‐MI, however, the source of that need more exploration.