Wainwright et al found mRNA expression of IL‐17A in human GBM18 and Hu et al further confirmed the higher expression of IL‐17 mRNA in 18 tumour tissues derived from out of 24 patients with malignant glioma than that in tissues derived from trauma patients, but there was no difference among various histologic grades of GBM.17 On the contrary, our results showed that IL‐17A expressions were significantly higher in WHO IV grade GBMs tissues than those in the WHO III, WHO I‐II and adjacent tissues. The gene discussed is IL17A; the disease is glioblastoma.