Research has indicated that β‐cells are particularly sensitive to glucolipotoxicity.10 In fact, pancreatic β‐cell dysfunction and death are two core features of the late stages of T2D.11 In diabetics, β‐cells secrete larger‐than‐normal amounts of insulin to overcome insulin resistance, causing overwork and overproduction of insulin for extended periods of time. The gene discussed is INS; the disease is type 2 diabetes mellitus.