BCR and B-cell chronic lymphocytic leukemia: Chronic lymphocytic leukaemia cells express high levels of BCR signalling‐activated T‐cell chemokines (such as CCL3, 4, 17, and 22), which are critical for creating a protective microenvironment.46, 47, 48 We, therefore, examined the effect of CUDC‐907 on these chemokines in response to BCR engagement (with anti‐IgM stimulation, which has been reported to induce CCL3/4 expression46).