Celastrol is a natural compound isolated from a Traditional Chinese Medicinal herb thunder god vine or Tripterygium wilfordii Hook F. which shows potent anti‐lung cancer activity through induction of CIP2A proteasomal degradation.32 To examine the combined effects of celastrol and EA, HOP62 and H1975 cells were treated with celastrol and/or EA and evaluated by the MTT assay. Here, CIP2A is linked to lung cancer.