EFNA3 and posterior cortical atrophy: For example, EFNA3 mRNA transcripts, whereas a detectable component of the PC3 EV cargo, appear not to be transferred at high abundance by EVs resulting from either bone-metastatic cell lines PC3 and C4-2-4B, but are transferred by C4-2, Further support for the presence of highly tailored PCa EV-RNA cargos is provided by our comparative analysis, which determined a significant enrichment of genes involved in key gene expression pathways (Fig. 4).