CD8A and neoplasm: Interestingly, in stage II–III colon carcinoma, a direct correlation between CD274 expression in tumor cells and CD8+ TILs (Table 2) was observed; 160 of 384 (41.9%) CD274-high tumors contained a high number of CD8+ TILs, and the remaining 223 (58.1%) CD274-high tumors had low CD8+ TILs.