CD274 and neoplasm: By Kaplan-Meier analysis of 5-year DFS, the following factors differed significantly between the two groups: pN stage (negative = 71% vs positive = 56%, p < 0.0001), the level of tumor membranous CD274 expression (high = 70% vs low = 57%, p = 0.0006, Fig. 3A) and the density of CD8+ TILs (high = 78% vs low = 57%, p < 0.0001, Fig. 3D).