The two main subtypes are alveolar rhabdomyosarcoma (ARMS), which is associated with PAX3/7-FOXO1 fusion genes, and embryonal rhabdomyosarcoma (ERMS), which is associated with mutations in common cancer genes such as HRAS, KRAS, NRAS, CTNNB1, PIK3CA and TP531. Here, HRAS is linked to alveolar rhabdomyosarcoma.