The C-reactive protein/albumin ratio (CRP/Alb ratio) is a novel inflammation-based marker and reported to perform promising prognostic value in hepatocellular carcinoma [6], clear cell renal cell carcinoma [7], small-cell lung cancer [8], esophageal squamous cell carcinoma [9], pancreatic cancer [10,11], and colorectal cancer [12]. The gene discussed is ALB; the disease is esophageal squamous cell carcinoma.