A previous study also found that patients with solid predominant subtype of ADC harboring EGFR mutations had significantly lower ORR (61% versus 88%, P = 0.03), shorter PFS (7.7 versus 13.5 months, P = 0.002) and OS (21.5 versus 31.0 months, P = 0.028) than those with non-solid predominant subtype of ADC [28]. The gene discussed is EGFR; the disease is AIDS dementia complex.