First, the meta-analysis of the association of GCKR with CAD depends to a large extent on the the combined UK Biobank, CARDIoGRAMplusC4D 1000 genomes-based GWAS, and Myocardial Infarction Genetics and CARDIoGRAM Exome dataset, which is actually a meta-analysis by itself [31]. Here, GCKR is linked to myocardial infarction.