NR5A1 and Premature ovarian insufficiency: Variants in the NR5A1 gene can cause a wide variety of DSDs including 46,XY gonadal dysgenesis, 46,XX premature ovarian insufficiency, and recently a single variant (p.Arg92Trp) has been implicated in 46,XX (ovo)testicular DSD (Baetens et al., 2017; Bashamboo et al., 2016; Domenice et al., 2016; Igarashi et al., 2017; Takasawa et al., 2017).