UGT1A1 and breast carcinoma: Although the mean UGT1A1 mRNA expression was not significantly different among ethnic groups, UGT1A1 mRNA expression levels was lower in breast cancer cases vs controls among EAs (Tumor: 0.3 ± 0.1; Normal: 3.2 ± 1.5, p = 0.002) (Figure 2A).