He presented with neonatal hypothyroidism, high PTH levels, normocalcemia, overweight but normal statural growth, gastroesophageal reflux, asthma, laryngomalacia, auricular septal defect, and macroglossia.21 Finally, a few cases of cardiac failure and convulsions likely due to hypocalcemia were reported; however, molecular diagnosis was rarely established.22, 23. The gene discussed is PTH; the disease is heart failure.