He presented with neonatal hypothyroidism, high PTH levels, normocalcemia, overweight but normal statural growth, gastroesophageal reflux, asthma, laryngomalacia, auricular septal defect, and macroglossia.21 Finally, a few cases of cardiac failure and convulsions likely due to hypocalcemia were reported; however, molecular diagnosis was rarely established.22, 23. This evidence concerns the gene PTH and gastroesophageal reflux disease.