JAK3 and autoimmune disease: For its specific contribution on the pathogenesis of uveitis, a specific study (Liao et al., 2018) on ankylosing spondylitis confirmed that the expression levels of JAK1 and JAK3 are positively correlated with various autoimmune diseases, including enthesitis, ankylosing spondylitis and uveitis, thereby validating their potential pathogenic contributions.