In an in vitro assay, the presence of WGP induced the differentiation of MO-MDSC into F4/80+ CD11c+ myeloid cells, serving as potent APCs and when injected intratumorally, WGP-treated MO-MDSCs were capable of inhibiting tumor growth in subcutaneously inoculated LLC (242). The gene discussed is ITGAX; the disease is neoplasm.