NFKB1 and nervous system disorder: In support of a likely role in cochlear protection, it has been suggested that NF-κB signaling plays a role in the effects of pioglitazone to protect against focal cerebral ischemia in rats (Zhang et al., 2011) and in several rodent models of neurological diseases (Nakamura et al., 2007; Park et al., 2007; Swanson et al., 2011).