PPARG and type 2 diabetes mellitus: The TZD drug pioglitazone, a PPARγ agonist approved by the FDA, is also known to decrease inflammatory mediators in patients with type 2 diabetes and coronary artery disease and to have favorable effects on vascular function (Wang et al., 2005; Forst et al., 2008; Cabrera et al., 2012; Kauppinen et al., 2013).