As expected, ARID1B-CSS patients more frequently displayed features associated with CSS than ARID1B-ID patients, including thick eyebrows, long eyelashes, thick alae nasi, long and/or broad philtrum, small nails and small or absent fifth distal phalanx, and hypertrichosis (p < 0.0001–0.001, Table 1). The gene discussed is ARID1B; the disease is Coffin-Siris syndrome.