CASP3 and hepatocellular carcinoma: Likewise, HCC-1569 cells demonstrated caspase 3/7 luminescence that was 3.89 ± 0.26 and 3.06 ± 0.18 fold higher when transfected with ASO 1a and 1b, respectively, than caspase 3/7 levels of HCC-1569 cells transfected with the control ASO (Fig. 3F).