Kaplan-Meier survival analysis revealed that depletion of Ars2 with shRNA significantly prolonged the survival time of the NOD/SCID mice bearing U87 glioblastoma cells compared with that of vector control shRNA (median survival of 42.2 ± 3.9 days for control shRNA versus 82.2 ± 16.5 days for Ars2 shRNA, P < 0.001) (Fig. 7A). Here, SRRT is linked to glioblastoma.