As displayed in Table 2, after correction for multiple testing (P ≤ 0.00625 considered as significant), the only significant association between APOE and risk of PSP that we observed occurred for the ε2/ε2 genotype when compared to all other genotypes; APOE ε2/ε2 was significantly more frequent in PSP compared to controls (1.3% vs. 0.4%, odds ratio (OR) = 4.41, P = 0.0057). The gene discussed is APOE; the disease is supranuclear palsy, progressive, 1.