PTEN and cancer: In the 20 cases analyzed, we detected three fusion events in known cancer driver genes (ATM in LUSC2; PTEN in LUSC1; WHSC1 in LUSC1), and a further seven events in candidate tumor-suppressor genes, including BOD1, DLG2, MBD2, and RBL1 (Fig. 2a,b; Supplementary Figure S4; Supplementary Table S2).