As a result of CD26 depletion through the transfection of interfering RNA, T-ALCL cells lost the ability to adhere to fibronectin and collagen I through the dephosphorylation of both integrin β1 and p38 mitogen-activated protein kinase (MAPK), which suppresses tumor development in in vivo xenograft models58. Here, MAPK14 is linked to neoplasm.