Using B220 and CD3 as general B and T cell markers respectively, we observed that mice in the hyperglycemia-only group (STZ + CON) showed a significant increase in the number of B cells (Fig. 2d), whilst those on high-fat diet (STZ + HFD) exhibited a significant decrease in the numbers of T cells compared to control (Fig. 2e). The gene discussed is PTPRC; the disease is Hyperglycemia.