For IL10–592 A > C, only the non-Asian populations under the allele contrast model (C vs A) (OR,4.34; 95%CI:1.87–10.07, I2:65%) and the recessive model (OR,2.1;95% CI,1.16–3.82,I2:0%) showed significant relationship between this SNP and the risk of AP (Fig. 3). This evidence concerns the gene IL10 and alkaline phosphatase measurement.