NDRG2 and B-cell chronic lymphocytic leukemia: Interestingly, we found that the expression level of miR-28-5p and miR-650 were significantly increased in CLL patients compared to HC, and were negatively associated with NDRG2. Furthermore, we examined the effects of antisense oligonucleotides targeting miR-28-5p and miR-650 on the primary CLL cells.