Furthermore, isorhamnetin was also found to inhibit gastric cancer cell invasion by modulating PPARγ signaling, and found to be suppressing inducible nitric oxide synthase (iNOS) expression and nitric oxide (NO) production in LPS-activated macrophages by inhibiting c-Jun N-terminal kinase (JNK)/nuclear factor of kappa light polypeptide gene enhance in B-cells inhibitor, alpha (IκBα)/(nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway [53]. The gene discussed is NOS2; the disease is gastric cancer.