This trial also reported that EPA + DPA supplementation rather than EPA alone could significantly reduce nile red staining of lipids in monocytes, and that both EPA + DPA and EPA alone significantly reduce monocytes surface markers CD11c, CD36, and CCR5, indicating that DPA might protect against atherosclerosis by inhibiting foamy monocyte formation and modulating monocyte phenotype [57]. The gene discussed is CD36; the disease is atherosclerosis.